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Regulatory Processes
Diseases
Protein Regulatory Pathways
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G-protein signaling_Ras family GTPases in kinase cascades (scheme) [score: 1 (0%)]
GTPases of the Ras superfamily are activated upon growth factors stimuli and controls
a wide range of essential biochemical pathways in all eukaryotic cells. One of the most
important functions of Ras proteins is activation of mitogen activated protein kinases
(MAPK). MAPK pathways are important ...
G-protein signaling_N-RAS regulation pathway [score: 1 (0%)]
Neuroblastoma RAS viral (v-ras) oncogene homolog (N-RAS)
belongs to Ras family of small GTPases. It serves as a signal transducer from growth
factor receptors and activates numerous effector molecules resulting in cell growth,
differentiation and survival [1], [
Transcription_CREB pathway [score: 1 (0%)]
Extracellular stimuli elicit changes in gene expression in target cells by activating
intracellular protein kinase cascades that phosphorylate transcription factors within the
nucleus. One of the best characterized stimulus-induced transcription factors is cyclic
AMP (cAMP) responsive element binding ...
Signal transduction_PTEN pathway [score: 1 (0%)]
Phosphatase and tensin homolog (PTEN) is a known tumor
suppressor. It inhibits growth factor-induced cell proliferation, division and regulates
Integrin-mediated cell adhesion and survival [1].
PTEN antagonizes Phosphoinositide-3-kinase
(PI3K), ...
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