IL-2 activation and signaling pathway
Interleukin-2 (IL-2) is a T-Cell-derived cytokine
important in the regulation of growth and differentiation of T-Cells, B-Cells, natural
killer cells, glioma cells, and cells of the monocyte lineage.
IL-2 signaling is mediated ...
IL-4 signaling pathway
Interleukin-4 (IL-4) is a T cell derived multifunctional cytokine
that plays a critical role in the regulation of immune responses. IL-4
induces Th2 (T helper 2) differentiation, ...
IL-9 signaling pathway
Interleukin-9 (IL-9) is a multifunctional cytokine secreted by T
helper 2 (Th2) lymphocytes. IL-9 exerts various effects on a
variety of cell types associated with allergic ...
Function of MEF2 in T lymphocytes.
Myocyte enhancer factors 2 (MEF2) is a family of muscle-enriched
transcription factors that have an essential role in myogenesis. In
addition, MEF2 is also ...
IL-12 signaling pathway
IL-12 is a key immunoregulatory cytokine
that coordinates innate and adaptive
immune response. ...
IL-12-induced IFN-gamma production
IL-12 is an important cytokine involved
in production of IFN-gamma by T cells and
NK cells, and plays an important ...