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G-protein signaling_N-RAS regulation pathway [score: 1 (0%)]
N-RAS regulation pathway
Neuroblastoma RAS viral (v-ras) oncogene homolog (
belongs to Ras family of small GTPases. It serves as a signal transducer from growth
factor receptors and activates numerous effector molecules resulting in cell growth,
differentiation and survival ...
Transcription_CREB pathway [score: 1 (0%)]
CREB signaling pathway
Extracellular stimuli elicit changes in gene expression in target cells
by activating intracellular protein kinase cascades that phosphorylate
transcription factors within the nucleus. ...
DNA damage_ATM/ATR regulation of G1/S checkpoint [score: 1 (0%)]
ATM/ATR regulation of G1/S and S/G2 checkpoints
DNA damage checkpoints are biochemical pathways that delay or arrest the
cell cycle progression in response to the DNA damage. All eukaryotic ...
Signal transduction_Erk Interactions: Inhibition of Erk [score: 1 (0%)]
Erk Interactions: Inhibition of Erk
Mitogen-activated protein kinase (MAPK) pathways regulate a variety of
physiological processes, such as cell growth, differentiation, and
apoptotic cell death. To date, ...
Cell cycle_Regulation of G1/S transition (part 2) [score: 1 (0%)]
Regulation of G1/S transition (part 2)
The commencement of the cell cycle coincides with the production and the
stabilization of the
Cyclin D. The D-type cyclins are essential
Signal transduction_AKT signaling [score: 1 (0%)]
RAC-alpha serine/threonine kinases (
AKTs) are crucial mediators
of various cellular process, such as apoptosis, regulation of cell
cycle, protein synthesis and regulation of metabolism. The ...
Signal transduction_PKA signaling [score: 1 (0%)]
Protein kinase cAMP-dependent (
PKA) is an enzyme playing key role
in a number of cellular processes. In its inactivated state, PKA
exists as a tetrameric complex of two catalytic ...
Signal transduction_PTEN pathway [score: 1 (0%)]
Phosphatase and tensin homolog (
PTEN) is a known tumor
suppressor. It inhibits growth factor-induced cell proliferation,
division and regulates Integrin-mediated cell adhesion ...