The haemostatic system maintains blood in a fluid state under normal conditions and responds to vessel injury by the rapid formation of a clot consisting of platelets and Fibrin. The traditional view of the regulation of blood coagulation is that the initiation phase is triggered by an extrinsic ...

Androgen and Estrogen receptors (Androgen receptor and ESR1 (nuclear)) function as steroid-hormone activated transcription factors. Upon binding the hormone ligand, receptors dissociate from accessory proteins, translocate into the nucleus, dimerize, and then stimulate transcription ...