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Signal transduction_Erk Interactions: Inhibition of Erk [score: 1 (0%)]
Mitogen-activated protein kinase (MAPK) pathways regulate a variety of physiological
processes, such as cell growth, differentiation, and apoptotic cell death. To date, three
MAPK pathways have been characterized in detail. The extracellular regulated kinase (ERK)
pathway is activated by a large ...
Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway [score: 1 (0%)]
The members of the tumour necrosis factor ligand family (TNFs) may induce both
apoptotic and anti-apoptotic pathways. TNFs transduces cellular responses through
activation of different TNF-receptors (TNFRs).
One important mechanism of cell survival is the activation of transcription of
different ...
Apoptosis and survival_Role of CDK5 in neuronal death and survival [score: 1 (0%)]
Cyclin-dependent kinase 5 (CDK5) is a member of the small
serine/threonine cyclin-dependent kinase (CDK) family.
The best known role of CDK5 is its regulatoin of the
cytoskeleton architecture of the central nervous system (CNS). There is also some
evidence that links CDK5 ...
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