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Development_Neurotrophin family signaling [score: 1 (0%)]
Factors of the neurotrophin family (NGF,
BDNF and neurotrophins NT-3 and
NT-4/5), promote neuronal survival or death. The best
characterized receptors for these trophic factors are the tropomyosin-related tyrosine
kinase receptors TrkA, TrkB,
and TrkC, ...
Apoptosis and survival_Role of CDK5 in neuronal death and survival [score: 1 (0%)]
Cyclin-dependent kinase 5 (CDK5) is a member of the small
serine/threonine cyclin-dependent kinase (CDK) family.
The best known role of CDK5 is its regulatoin of the
cytoskeleton architecture of the central nervous system (CNS). There is also some
evidence that links CDK5 ...
Manganese, Calcium and Iron-regulated proteins [score: 1 (0%)]
Proteins, regulated by binding of inorganic ions, are very important for different
aspects of cell functioning.
There is a wide variety of Calcium, Manganese and Iron-regulated proteins inside and
out of the cells.
Binding of Ca('2+) extracellular region to receptors of
L-Glutamic ...
Selected targets of SP1 [score: 1 (0%)]
Sp1 transcription factor (SP1) is a transcription factor
involved in gene expression in the early development of an organism. It belongs to the
Sp/KLF family of transcription factors. The SP1
transcription factor contains a zinc finger protein motif, by which it binds directly to
DNA ...
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