Phosphatase and tensin homolog (PTEN) is a known tumor suppressor. It inhibits growth factor-induced cell proliferation, division and regulates Integrin-mediated cell adhesion and survival [1].

Erythropoiesis is a major pathway by which a pluripotent hematopoietic stem cell gives rise to mature end stage cells. Erythropoietin (EPO) is a lineage-specific hematopoietic growth factor required for survival, proliferation and differentiation of committed erythroid progenitor cells [