 |
|
Refine By Categories
Regulatory Processes
Diseases
Protein Regulatory Pathways
|
 |
|
 |
|
|
Results
|
|
|
 |
| Showing 1 - 6 out of 6 |
Result pages:
1 |
|
Signal transduction_IP3 signaling [score: 1 (0%)]
Efficient and coordinated synthesis of the second messengers, including
Inositol-1,4,5-trisphosphate (IP3), Diacylglycerol
(DAG), and
Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3), is
necessary for normal cell functioning. Production of secondary messengers is regulated ...
Apoptosis and survival_BAD phosphorylation [score: 1 (0%)]
BAD is a member of the BCL-2 family. BCL-2 family members
are regulators of the programmed cell death pathways.
BAD induces apoptosis by inhibiting antiapoptotic
BCL-2-family members - BCL-x,
Bcl-2, thereby allowing two other pro-apoptotic proteins,
BAK ...
Signal transduction_PTEN pathway [score: 1 (0%)]
Phosphatase and tensin homolog (PTEN) is a known tumor
suppressor. It inhibits growth factor-induced cell proliferation, division and regulates
Integrin-mediated cell adhesion and survival [1].
PTEN antagonizes Phosphoinositide-3-kinase
(PI3K), ...
Development_EPO-induced Jak-STAT pathway [score: 1 (0%)]
Erythropoiesis is a major pathway by which a pluripotent hematopoietic stem cell gives
rise to mature end stage cells. Erythropoietin (EPO) is a
lineage-specific hematopoietic growth factor required for survival, proliferation and
differentiation of committed erythroid progenitor cells [
Transcription_Androgen Receptor nuclear signaling [score: 1 (0%)]
Androgen is the active metabolic product,
5alpha-Dihydrotestosterone, which is produced from the
transformation of Testosterone catalyzed by the
Steroid-5-alpha-reductase, alpha polypeptides 1 and 2 (S5AR1
and S5AR2) [1], [2]. ...
Development_Flt3 signaling [score: 1 (0%)]
FMS-like tyrosine kinase 3 (FLT3) belongs to the
subclass III family of receptor tyrosine kinases and it is expressed mainly in early
myeloid and lymphoid progenitor cells. Its activation leads mainly to proliferation and
survival [1], [2]. ...
|
|
|
|
|