33
Refine By Categories
Regulatory Processes
Home > Products & Services > Biomarker Center of Excellence > BioPathways >
Results
Showing 21 - 30 out of 31 Result pages:   Prev 1 2 3 4 Next
Apoptosis and survival_Role of CDK5 in neuronal death and survival [score: 1 (0%)]

Cyclin-dependent kinase 5 (CDK5) is a member of the small serine/threonine cyclin-dependent kinase (CDK) family.

The best known role of CDK5 is its regulatoin of the cytoskeleton architecture of the central nervous system (CNS). There is also some evidence that links CDK5 ...

Apoptosis and survival_APRIL and BAFF signaling [score: 1 (0%)]

Tumor necrosis factor (ligand) superfamily members 13 and 13b (APRIL and BAFF) and their receptors - Tumor necrosis factor receptor superfamily members 13C, 17 and 13B (BAFF-R, BCMA and TACI) - play important roles in the B-cell and T-cell arms of the immune system ...

Bacterial infections in CF airways [score: 1 (0%)]

The upper airways represent a primary site for the introduction of pathogenic microorganisms from inspired air. The ciliated epithelium features several powerful mechanisms for prevention of colonization by inhaled bacteria, thus the lower respiratory tract usually remains sterile [1].

Defective ...

Apoptosis and survival_Anti-apoptotic action of membrane-bound ESR1 [score: 1 (0%)]

Estradiol exerts an anti-apoptotic effect on a wide variety of tissues. Estradiol as classical steroid hormone diffuses through plasma membrane, activates ESR1 ...

Apoptosis and survival_Anti-apoptotic action of nuclear ESR1 and ESR2 [score: 1 (0%)]

Estradiol exerts an anti-apoptotic effect on a wide variety of tissues that is mediated via activation of nuclear form of ESR1 (nuclear) and ESR2

Manganese, Calcium and Iron-regulated proteins [score: 1 (0%)]

Proteins, regulated by binding of inorganic ions, are very important for different aspects of cell functioning.

There is a wide variety of Calcium, Manganese and Iron-regulated proteins inside and out of the cells.

Binding of Ca('2+) extracellular region to receptors of L-Glutamic ...

Selected targets of Androgen and Estrogen receptors [score: 1 (0%)]

Androgen and Estrogen receptors (Androgen receptor and ESR1 (nuclear)) function as steroid-hormone activated transcription factors. Upon binding the hormone ligand, receptors dissociate from accessory proteins, translocate into the nucleus, dimerize, and then stimulate transcription ...

Selected targets of SP1 [score: 1 (0%)]

Sp1 transcription factor (SP1) is a transcription factor involved in gene expression in the early development of an organism. It belongs to the Sp/KLF family of transcription factors. The SP1 transcription factor contains a zinc finger protein motif, by which it binds directly to DNA ...

Selected targets of C/EBP [score: 1 (0%)]

CCAAT/enhancer binding proteins (C/EBP) are a group of bZIP transcription factors, consisting of C/EBPalpha, beta, delta, epsilon, gamma and zeta, which can bind as homodimers to certain promoters and enhancers. C/EBP is important in the regulation ...

Selected targets of NRSF [score: 1 (0%)]

RE1-silencing transcription factor (NRSF) is a member of the Kruppel-type zinc finger transcription factor family. It is a transcriptional repressor of neuronal genes in non-neuronal tissues. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer ...

Result pages:   Prev 1 2 3 4 Next
Home | Animal Welfare | Privacy Policy | Contact Us | Site Map | Investigators | Covance.Asia
RSS © Copyright 2013 Covance Inc. All rights reserved.