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Protein Regulatory Pathways
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Development_HGF signaling pathway [score: 1 (0%)]
Hepatocyte growth factor/Scatter factor (HGF) is a
multifunctional growth factor which induces cell dissociation, migration, protection from
apoptosis, proliferation and differentiation [1]. Receptor Met
proto-oncogene (HGF receptor (Met))
has tyrosine-kinase ...
Development_ERBB-family signaling [score: 1 (0%)]
The ERBB family of receptor tyrosine kinases consists of
four closely related members: Epidermal growth factor receptor
(EGFR, also known as ERBB1), v-erb-b2 erythroblastic
leukemia viral oncogene homolog 2, 3 and 4 (ERBB2,
ERBB3, and ERBB4). Binding of
extracellular ...
Development_Ligand-independent activation of ESR1 and ESR2 [score: 1 (0%)]
In addition to the conventional hormone-dependent regulation of activity of Estrogen
receptor alpha and beta (ESR1(nuclear) and
ESR2 respectively), there is a cross-talk between signal transduction
pathways and estrogen receptors [1]. Epidermal growth factor
(EGF), ...
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