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Development_FGFR signaling pathway [score: 1 (0%)]
FGFR signaling pathway
Fibroblast growth factor 2 (FGF2) has been implicated in
diverse cellular processes, including apoptosis, cell survival, chemotaxis, cell
adhesion, migration, differentiation, and proliferation [1].
FGF2 induces ...
Cytoskeleton remodeling_Reverse signaling by ephrin B [score: 1 (0%)]
Reverse signaling by Ephrin B
Ephrin receptors and Ephrins
are both membrane bound, and following their interaction and clustering, each can
transduce signals that regulate cell responses [1].
Ephrin receptors activate reverse ...
Development_HGF signaling pathway [score: 1 (0%)]
HGF signaling
Hepatocyte growth factor/Scatter factor (HGF) is a
multifunctional growth factor which induces cell dissociation, migration, protection from
apoptosis, proliferation and differentiation [1]. Receptor Met
proto-oncogene (HGF receptor ...
Development_ERBB-family signaling [score: 1 (0%)]
ERBB-family signaling
The ERBB family of receptor tyrosine kinases consists of
four closely related members: Epidermal growth factor receptor
(EGFR, also known as ERBB1), v-erb-b2 erythroblastic
leukemia viral oncogene homolog 2, 3 and 4 (ERBB2,
ERBB3, and ...
Development_IGF-1 receptor signaling [score: 1 (0%)]
IGF-R1 signaling
The insulin-like growth factor system (IGF system) comprises two receptors:
Insulin-like growth factor 1 receptor (IGF-1 receptor) and
IGF-IIR with their respective ligands: Insulin-like growth factors 1 and 2
(IGF-1 and IGF-2) and six
high-affinity ...
Transcription_PPAR Pathway [score: 1 (0%)]
PPAR Pathway
Peroxisome Proliferator-Activated Receptors (PPAR) are
ligand-inducible transcription factors that belong to the nuclear
hormone receptor superfamily. The PPAR group consists of ...
Chemotaxis_CXCR4 signaling pathway [score: 1 (0%)]
CXCR4 signaling via small GTPases
Chemokine (C-X-C motif) receptor-4 (CXCR4) is a G
protein-coupled receptor (GPCR). It is the only known receptor for stromal-derived
factor-1 (SDF-1), and SDF-1 is
the only known ligand for CXCR4 [1].
The ...
Development_EGFR signaling via PIP3 [score: 1 (0%)]
EGFR signaling via PIP3
The Epidermal growth factor receptor (EGFR) belongs to
the ERBB family of receptor tyrosine kinases, which consists of four closely related
members: EGFR and v-erb-b2 erythroblastic leukemia viral
oncogene homolog 2, neuro/glioblastoma derived oncogene ...
Development_EGFR signaling via small GTPases [score: 1 (0%)]
EGFR signaling via small GTPase
The Epidermal growth factor receptor (EGFR) belongs to
the ERBB family of receptor tyrosine kinases, which consists of four closely related
members: EGFR and v-erb-b2 erythroblastic leukemia viral
oncogene homolog 2, neuro/glioblastoma derived ...
Cell adhesion_ECM remodeling [score: 1 (0%)]
ECM remodeling
Extracellular matrix (ECM) remodeling is involved in normal physiological processes,
such as embryonic development, reproduction, proliferation, cell motility and adhesion,
wound healing, angiogenesis, as well as in disease processes, such as arthritis and
metastasis. ...
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