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Cytokine production by Th17 cells in CF [score: 1 (0%)]
Cystic Fibrosis (CF) is a potentially lethal genetic disease that typically results in
the development of bronchial inflammation, bronchiectasis, the progressive loss of lung
function and, ultimately, death [1].
CF is caused by genetic defects in Cystic Fibrosis ...
Immune response_Bacterial infections in normal airways [score: 1 (0%)]
The upper airways represent a primary site for the introduction of pathogenic
microorganisms from inspired air. The ciliated epithelium features several powerful
mechanisms for prevention of colonization by inhaled bacteria, thus the lower respiratory
tract usually remains sterile. Toll-like receptors ...
Selected targets of SP1 [score: 1 (0%)]
Sp1 transcription factor (SP1) is a transcription factor
involved in gene expression in the early development of an organism. It belongs to the
Sp/KLF family of transcription factors. The SP1
transcription factor contains a zinc finger protein motif, by which it binds directly to
DNA ...
Selected targets of c-Myc [score: 1 (0%)]
V-myc myelocytomatosis viral oncogene homolog (c-Myc) is
a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression,
apoptosis and cellular transformation. c-Myc controls the
transcription of a variety of different targets and regulates different processes, ...
Selected targets of C/EBP [score: 1 (0%)]
CCAAT/enhancer binding proteins (C/EBP) are a group of
bZIP transcription factors, consisting of C/EBPalpha,
beta, delta,
epsilon, gamma and
zeta, which can bind as homodimers to certain promoters and
enhancers. C/EBP is important in the regulation ...
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