Cystic Fibrosis (CF) is a potentially lethal genetic disease that typically results in the development of bronchial inflammation, bronchiectasis, ...

The upper airways represent a primary site for the introduction of pathogenic microorganisms from inspired air. The ciliated epithelium features several powerful mechanisms ...

Cystic Fibrosis (CF) is a potentially lethal genetic disease that typically results in the development of bronchial inflammation, bronchiectasis, the ...

Transport vesicles are classified according to the components of the protein coat that surrounds them during their genesis and early life cycle of endocytosis. One of the most common ...

Sp1 transcription factor (SP1) is a transcription factor involved in gene expression in the early development of an organism. It belongs to the Sp/KLF family of transcription factors. The SP1 transcription factor contains a zinc ...

V-myc myelocytomatosis viral oncogene homolog (c-Myc) is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. c-Myc controls the transcription of a variety of different targets ...

CCAAT/enhancer binding proteins (C/EBP) are a group of bZIP transcription factors, consisting of C/EBPalpha, beta, delta, epsilon, gamma and zeta, which can bind as homodimers to certain promoters and enhancers. ...

Hepatocyte nuclear factors (HNFs) are a group of phylogenetically unrelated transcription factors that regulate the transcription of a diverse group of genes. ...