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Development_Activation of ERK by Alpha-1 adrenergic receptors [score: 1 (0%)]

Subtype alpha-1 adrenergic receptors consists of Alpha-1A adrenergic receptor, Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor. They participate in many physiological processes via different pathways. One of the best studied alpha-1 adrenergic receptors-stimulated ...

2-Naphthylamine and 2-Nitronaphtalene metabolism [score: 1 (0%)]

Metabolism and binding studies with 2-Naphthylamine and many other arylamines have shown cytochrome P-450 catalysed N-hydroxylation to be a critical step in the activation of these compounds. Followed by glucuronidation and excretion of the glucuronides via the kidney, this reaction can account ...

Naphthalene metabolism [score: 1 (0%)]

Toxicity of Naphthalene in cell culture and animal models has to do with metabolisation of this compound by cytochrome P450 monooxygenases. Deactivation of Naphthalene involves epoxidation followed by glutathione conjugation and mercapturic acid formation [1]. Naphthalene ...

Transport_Clathrin-coated vesicle cycle [score: 1 (0%)]

Transport vesicles are classified according to the components of the protein coat that surrounds them during their genesis and early life. One of the most common and probably best-characterized classes of coated vesicle is that comprising three-layered Clathrin-coated ...

Lipase family functions [score: 1 (0%)]

Lipases are water-soluble enzymes that catalyze the hydrolysis of ester chemical bonds in water-insoluble lipid substrates. Lipases are widely distributed in animals, plants and prokaryotes. The lipase family consists of triglyceride lipases, phospholipases and sphingomyelinases. By the place of ...

Manganese, Calcium and Iron-regulated proteins [score: 1 (0%)]

Proteins, regulated by binding of inorganic ions, are very important for different aspects of cell functioning.

There is a wide variety of Calcium, Manganese and Iron-regulated proteins inside and out of the cells.

Binding of Ca('2+) extracellular region to receptors of L-Glutamic ...

Fructose metabolism [score: 1 (0%)]

D-Sucrose and Glycogen are the primary sources of D-fructose synthesis.

D-Sucrose is hydrolyzed to D-fructose and D-Glucose by Maltase-glucoamylase (MGAM) and Sucrase-isomaltase (SUIS) [1]. Ketohexokinase (KHK) ...

L-Arginine, L-Alanine, L-Aspartic acid and Creatine metabolism [score: 1 (0%)]

Metabolism of L-Arginine, L-Alanine, L-Aspartic acid and Creatine is part of the urea cycle.

The urea cycle represents the set of conversion reactions of ammonia, a toxic product of oxidative deamination reactions, into Urea, a relatively nontoxic excretion product of nitrogen metabolism ...

Selected targets of SP1 [score: 1 (0%)]

Sp1 transcription factor (SP1) is a transcription factor involved in gene expression in the early development of an organism. It belongs to the Sp/KLF family of transcription factors. The SP1 transcription factor contains a zinc finger protein motif, by which it binds directly to DNA ...

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