Retinoid receptors are asymmetrically oriented Retinoic acid receptor (RAR)/ Retinoid
X receptor (RXR) heterodimers that bind to specific DNA sequences or Retinoic acid
response elements (RAREs) in the promoters of a large number of retinoid-target genes
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Key enzymes involved in retinoid metabolisms are alcohol and aldehyde dehydrogenases
that convert retinols to aldehydes and aldehydes to carboxylic acids, respectively. The
first oxidation reaction is catalyzed by a large number of enzymes from the
Dehydrogenase/reductase (SDR family), and by classic ...