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Protein Regulatory Pathways
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| Showing 11 - 17 out of 17 |
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Role of CDK5 in neuronal cell function [score: 1 (0%)]
Cyclin-dependent kinase 5 (CDK5) is a member of the small
serine/threonine cyclin-dependent kinase family.
CDK5 is abundantly expressed in the adult brain.
Moreover, it is present in subcellular fractions enriched for synaptic membranes, and
localize to pre- and postsynaptic ...
Regulation and function of Amyloid proteins [score: 1 (0%)]
Amyloid precursor protein (APP) was initially detected in
cells of the central nervous system and is considered to be involved in the pathogenesis
of Alzheimer's disease [1]. Since then, APP has
been found in peripheral organs where it plays a variety of ...
Regulation of GABA signaling by Nicotine acetylcholine receptors [score: 1 (0%)]
Nicotinic acetylcholine receptors (nAChR) are cholinergic
receptors that form ligand-gated ion channels in the plasma membranes of certain neurons
and on the postsynaptic side of the neuromuscular junctions. As ionotropic receptors,
nAChR are directly linked to ion channels and do not ...
PXR/ RXR regulation of ATP-binding transporters [score: 1 (0%)]
ATP-binding transporters are transmembrane proteins that utilize the energy of
adenosine triphosphate (ATP) hydrolysis to carry out certain biological processes
including translocation of various substrates across membranes. They transport a variety
of substrates across extra- and intracellular membranes, ...
Manganese, Calcium and Iron-regulated proteins [score: 1 (0%)]
Proteins, regulated by binding of inorganic ions, are very important for different
aspects of cell functioning.
There is a wide variety of Calcium, Manganese and Iron-regulated proteins inside and
out of the cells.
Binding of Ca('2+) extracellular region to receptors of
L-Glutamic ...
Selected targets of SP1 [score: 1 (0%)]
Sp1 transcription factor (SP1) is a transcription factor
involved in gene expression in the early development of an organism. It belongs to the
Sp/KLF family of transcription factors. The SP1
transcription factor contains a zinc finger protein motif, by which it binds directly to
DNA ...
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