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G-protein signaling_Ras family GTPases in kinase cascades (schema) [score: 1 (0%)]
Ras family GTPases in kinase cascades

GTPases of the Ras superfamily are activated upon growth factors stimuli and controls a wide range of essential biochemical pathways in all eukaryotic cells. One of the most ...

G-protein signaling_N-RAS regulation pathway [score: 1 (0%)]

N-RAS regulation pathway

Neuroblastoma RAS viral (v-ras) oncogene homolog (N-RAS) belongs to Ras family of small GTPases. It serves as a signal transducer from growth factor receptors and activates numerous effector molecules resulting in cell growth, differentiation and survival ...

Transcription_CREB pathway [score: 1 (0%)]
CREB signaling pathway

Extracellular stimuli elicit changes in gene expression in target cells by activating intracellular protein kinase cascades that phosphorylate transcription factors within the nucleus. One of the best characterized stimulus-induced transcription factors ...

DNA damage_ATM/ATR regulation of G1/S checkpoint [score: 1 (0%)]

ATM/ATR regulation of G1/S and S/G2 checkpoints

DNA damage checkpoints are biochemical pathways that delay or arrest the cell cycle progression in response to the DNA damage. All eukaryotic ...

Signal transduction_Erk Interactions: Inhibition of Erk [score: 1 (0%)]

Erk Interactions: Inhibition of Erk

Mitogen-activated protein kinase (MAPK) pathways regulate a variety of physiological processes, such as cell growth, differentiation, and apoptotic cell death. To date, ...

Cell cycle_Regulation of G1/S transition (part 2) [score: 1 (0%)]

Regulation of G1/S transition (part 2)

The commencement of the cell cycle coincides with the production and the stabilization of the Cyclin D. The D-type cyclins are essential ...

Cell cycle_Regulation of G1/S transition (part 1) [score: 1 (0%)]

Regulation of G1/S transition (part 1)

DNA damage checkpoints are biochemical pathways that delay or halt cell cycle progression in response ...

Signal transduction_AKT signaling [score: 1 (0%)]
AKT signaling

RAC-alpha serine/threonine kinases (AKTs) are crucial mediators of various cellular process, such as apoptosis, regulation of cell cycle, protein synthesis and regulation of metabolism. The ...

Signal transduction_PKA signaling [score: 1 (0%)]

PKA signaling

Protein kinase cAMP-dependent (PKA) is an enzyme playing key role in a number of cellular processes. In its inactivated state, PKA exists as a tetrameric complex of two catalytic ...

Signal transduction_PTEN pathway [score: 1 (0%)]

PTEN pathway

Phosphatase and tensin homolog (PTEN) is a known tumor suppressor. It inhibits growth factor-induced cell proliferation, division and regulates Integrin-mediated cell adhesion ...

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