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Development_Alpha-2 adrenergic receptor activation of ERK [score: 1 (0%)]

Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, and Alpha-2C-1 adrenergic receptor participate in activation of Mitogen-activated protein kinases 1 and 3 (ERK1/2) via different ways [1].

Alpha-2A adrenergic receptor ...

Development_Dopamine D2 receptor transactivation of EGFR [score: 1 (0%)]

Dopamine is a major transmitter and neuromodulator in the CNS. This transmitter mediates its signaling through GPCRs of which the Dopamine D2 receptor class of ...

Development_ACM2 and ACM4 activation of ERK [score: 1 (0%)]

ACM2 and ACM4 act via Guanine nucleotide binding proteins (G-protein) of G-protein alpha-i family. ACM2 can activate ...

Manganese, Calcium and Iron-regulated proteins [score: 1 (0%)]

Proteins, regulated by binding of inorganic ions, are very important for different aspects of cell functioning.

There is a wide variety of Calcium, Manganese and Iron-regulated proteins inside and out of the cells.

Binding of Ca('2+) extracellular region to receptors of L-Glutamic ...

Selected targets of SP1 [score: 1 (0%)]

Sp1 transcription factor (SP1) is a transcription factor involved in gene expression in the early development of an organism. It belongs to the Sp/KLF family of transcription factors. The SP1 transcription factor contains a zinc finger protein motif, by which it binds directly to DNA ...

Selected targets of c-Myc [score: 1 (0%)]

V-myc myelocytomatosis viral oncogene homolog (c-Myc) is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. c-Myc controls the transcription of a variety of different targets and regulates different processes, ...

Selected targets of EGR1 [score: 1 (0%)]

Early growth response 1 (EGR1) and Early growth response 2 (EGR2 (Krox20)) belong to the EGR family of C2H2-type zinc-finger proteins, which function as a transcriptional regulators.

EGR1 activates a wide variety of different targets, which are required for cell proliferation, ...

Selected targets of C/EBP [score: 1 (0%)]

CCAAT/enhancer binding proteins (C/EBP) are a group of bZIP transcription factors, consisting of C/EBPalpha, beta, delta, epsilon, gamma and zeta, which can bind as homodimers to certain promoters and enhancers. C/EBP is important in the regulation ...

Selected targets of CREB1 [score: 1 (0%)]

cAMP responsive element binding protein 1 (CREB1) is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. CREB1 binds as a homodimer to the cAMP-responsive element, an octameric palindrome. CREB1 is phosphorylated by several protein kinases, ...

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