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Proteolysis_Role of Parkin in the Ubiquitin-Proteasomal Pathway [score: 1 (0%)]
Parkin is E3-ubiquitin-protein ligase that ubiquitinates
itself and specific substrate proteins playing a protective role by sequestering
misfolded proteins [1].
E3 ligases are part of the cellular machinery that tags proteins with ubiquitin,
thereby targeting ...
Regulation and function of Amyloid proteins [score: 1 (0%)]
Amyloid precursor protein (APP) was initially detected in
cells of the central nervous system and is considered to be involved in the pathogenesis
of Alzheimer's disease [1]. Since then, APP has
been found in peripheral organs where it plays a variety of ...
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