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Development_Neurotrophin family signaling [score: 1 (0%)]
Neurotrophin family signaling
Factors of the neurotrophin family (
NGF, BDNF and
neurotrophins NT-3 and NT-4/5), promote neuronal survival
or death. The best characterized receptors ...
Proteolysis_Role of Parkin in the Ubiquitin-Proteasomal Pathway [score: 1 (0%)]
Role of Parkin in the Ubiquitin-Proteasomal
Parkin is E3-ubiquitin-protein ligase that ubiquitinates
itself and specific substrate proteins playing a protective role by sequestering
misfolded proteins [ 1].
E3 ligases are part of the ...
Development_Alpha-2 adrenergic receptor activation of ERK [score: 1 (0%)]
Alpha-2 adrenergic receptor activation of
Alpha-2A adrenergic receptor, Alpha-2B
adrenergic receptor, and Alpha-2C-1 adrenergic
receptor participate in activation of Mitogen-activated protein kinases 1
and 3 ( ERK1/2) via different ways [ 1]. Alpha-2A ...
Role of CDK5 in neuronal cell function [score: 1 (0%)]
Role of CDK5 in neuronal cell function
Cyclin-dependent kinase 5 (
CDK5) is a member of the small
serine/threonine cyclin-dependent kinase family. CDK5 is abundantly expressed in the adult brain.
Moreover, it is present in subcellular fractions enriched for synaptic ...
Regulation and function of Amyloid proteins [score: 1 (0%)]
Regulation and function of Amyloid
Amyloid precursor protein (
APP) was initially detected in
cells of the central nervous system and is considered to be involved in the pathogenesis
of Alzheimer's disease [ 1]. Since then, APP has
Manganese, Calcium and Iron-regulated proteins [score: 1 (0%)]
Manganese, Calcium and Iron-regulated
Proteins, regulated by binding of inorganic ions, are very important for different
aspects of cell functioning.
There is a wide variety of Calcium, Manganese and Iron-regulated proteins inside and
out of the cells.