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Development_EGFR signaling pathway [score: 1 (0%)]

Epidermal growth factor receptor (EGFR) belongs to the ERBB family of receptor tyrosine kinases that contains four closely related members EGFR and ERBB2-4. They couple the binding of the extracellular growth factor ligands to intracellular signaling pathways that regulate diverse ...

Immune response_IL-6 signaling pathway [score: 1 (0%)]

Interleukin-6 (IL-6) is a pleiotropic cytokine produced by various types of lymphoid and nonlymphoid cells, such as T cells, B cells, monocytes, fibroblasts, keratinocytes, endothelial cells, mesangial cells and several tumor cells. IL-6 provokes a broad range of cellular and physiological responses, ...

Immune response_MIF-mediated glucocorticoid regulation [score: 1 (0%)]

Glucocorticoids are potent anti-inflammatory and immunosuppressive agents. They inhibit synthesis of almost all known cytokines, enzymes involved in the inflammatory process and several cell surface molecules required for immune function. Glucocorticoids mediate these effects via the ...

Immune response_Oncostatin M signaling via MAPK in human cells [score: 1 (0%)]

Oncostatin M is a multifunctional cytokine produced by activated T lymphocytes, monocytes and microglia. It is structurally and functionally related to the subfamily of hematopoietic and neurotrophic cytokines known as the Interleukin 6 (IL6)-type cytokine family [1].

Human ...

Apoptosis and survival_Anti-apoptotic action of nuclear ESR1 and ESR2 [score: 1 (0%)]

Estradiol exerts an anti-apoptotic effect on a wide variety of tissues that is mediated via activation of nuclear form of ESR1 (nuclear) and ESR2

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