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Immune response_IL-22 signaling pathway [score: 1 (0%)]

Interleukin-22 (IL-22) is a member of the IL-10 family of cytokines. The major sources of IL-22 are activated T cells, especially upon type 1 polarization, and natural killer (NK) cells [1], [2].

IL-22 acts via a ...

Immune response_Oncostatin M signaling via MAPK in human cells [score: 1 (0%)]

Oncostatin M is a multifunctional cytokine produced by activated T lymphocytes, monocytes and microglia. It is structurally and functionally related to the subfamily of hematopoietic and neurotrophic cytokines known as the Interleukin 6 (IL6)-type cytokine family [1].

Human ...

Immune response_IL-12-induced IFN-gamma production [score: 1 (0%)]

IL-12 is an important cytokine involved in production of IFN-gamma by T cells and NK cells, and plays an important role in T-helper ...

Selected targets of SP1 [score: 1 (0%)]

Sp1 transcription factor (SP1) is a transcription factor involved in gene expression in the early development of an organism. It belongs to the Sp/KLF family of transcription factors. The SP1 transcription factor contains a zinc finger protein motif, by which it binds directly to DNA ...

Selected targets of C/EBP [score: 1 (0%)]

CCAAT/enhancer binding proteins (C/EBP) are a group of bZIP transcription factors, consisting of C/EBPalpha, beta, delta, epsilon, gamma and zeta, which can bind as homodimers to certain promoters and enhancers. C/EBP is important in the regulation ...

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