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Transcription_NF-kB activation pathways [score: 1 (0%)]
NF-kB activation pathways
NF-kB activation in response to different stimuli are broadly classified as the canonical and non-canonical pathways, depending on whether activation involves I-kB degradation or NF-kB2 (p100) processing. ...
Immune response_IL-2 activation and signaling pathway [score: 1 (0%)]
IL-2 activation and signaling pathway
IL-2) is a T-Cell-derived cytokine
important in the regulation of growth and differentiation of T-Cells, B-Cells, natural
killer cells, glioma cells, and cells of the monocyte lineage. IL-2 signaling is mediated ...
Immune response_IL-4 signaling pathway [score: 1 (0%)]
IL-4 signaling pathway
IL-4) is a T cell derived multifunctional cytokine
that plays a critical role in the regulation of immune responses. IL-4
induces Th2 (T helper 2) differentiation, ...
Immune response _IFN gamma signaling pathway [score: 1 (0%)]
Interferons (IFNs) are pleiotropic cytokines that mediate anti-viral
responses, inhibit proliferation and participate in immune surveillance
and tumor suppression by inducing the ...
Immune response_T cell receptor signaling pathway [score: 1 (0%)]
T cell receptor signaling pathway
T cell receptors
(TCR) play a key role in functioning of T cells
and formation of the immunological synapse. It provides connection
between T cell and the antigen-presenting ...
Immune response_Alternative complement pathway [score: 1 (0%)]
Alternative complement pathway
Complement system is a major effector of humoral branch of the immune
system, acting to protect the host from microorganisms, such as bacteria.
Complement components ...
Immune response_IL-6 signaling pathway [score: 1 (0%)]
IL-6 signaling pathway
IL-6) is a pleiotropic cytokine produced by
various types of lymphoid and nonlymphoid cells, such as T cells, B
cells, monocytes, fibroblasts, keratinocytes, ...
Development_Notch Signaling Pathway [score: 1 (0%)]
Notch Signaling Pathway
Notch homolog 1 translocation-associated (
NOTCH1) is synthesized
as NOTCH1 precursor, which is cleaved by Furin to NOTCH1
receptor form. NOTCH1 ...
Immune response_MIF in innate immunity response [score: 1 (0%)]
MIF in innate immunity response
The cytokine Macrophage migration inhibitory factor (
MIF) is an
integral mediator of the innate immune system. Monocytes, macrophages
and lymphocytes constitutively ...