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Transcription_NF-kB activation pathways [score: 1 (0%)]
NF-kB activation pathways Abstract:

Pathways of NF-kB activation in response to different stimuli are broadly classified as the canonical and non-canonical pathways, depending on whether activation involves I-kB degradation or NF-kB2 (p100) processing. ...

Immune response_IL-2 activation and signaling pathway [score: 1 (0%)]

IL-2 activation and signaling pathway

Interleukin-2 (IL-2) is a T-Cell-derived cytokine important in the regulation of growth and differentiation of T-Cells, B-Cells, natural killer cells, glioma cells, and cells of the monocyte lineage.

IL-2 signaling is mediated ...

Immune response_IL-4 signaling pathway [score: 1 (0%)]

IL-4 signaling pathway

Interleukin-4 (IL-4) is a T cell derived multifunctional cytokine that plays a critical role in the regulation of immune responses. IL-4 induces Th2 (T helper 2) differentiation, ...

Immune response _IFN gamma signaling pathway [score: 1 (0%)]

Interferon-gamma signaling

Interferons (IFNs) are pleiotropic cytokines that mediate anti-viral responses, inhibit proliferation and participate in immune surveillance and tumor suppression by inducing the ...

Immune response_T cell receptor signaling pathway [score: 1 (0%)]

T cell receptor signaling pathway

T cell receptors (TCR) play a key role in functioning of T cells and formation of the immunological synapse. It provides connection between T cell and the antigen-presenting ...

Immune response_Alternative complement pathway [score: 1 (0%)]

Alternative complement pathway

Complement system is a major effector of humoral branch of the immune system, acting to protect the host from microorganisms, such as bacteria.

Complement components ...

Immune response_IL-6 signaling pathway [score: 1 (0%)]

IL-6 signaling pathway

Interleukin-6 (IL-6) is a pleiotropic cytokine produced by various types of lymphoid and nonlymphoid cells, such as T cells, B cells, monocytes, fibroblasts, keratinocytes, ...

Development_Notch Signaling Pathway [score: 1 (0%)]

Notch Signaling Pathway

Notch homolog 1 translocation-associated (NOTCH1) is synthesized as NOTCH1 precursor, which is cleaved by Furin to NOTCH1 receptor form. NOTCH1 ...

Development_NOTCH1-mediated pathway for NF-KB activity modulation [score: 1 (0%)]

NOTCH1-mediated pathway for NF-KB activity modulation

Interleukin 1 (IL-1) activates Nuclear factor of kappa light polypeptide gene enhancer in B-cells (NF-KB) via Interleukin-1 receptor-associated ...

Immune response_MIF in innate immunity response [score: 1 (0%)]

MIF in innate immunity response

The cytokine Macrophage migration inhibitory factor (MIF) is an integral mediator of the innate immune system. Monocytes, macrophages and lymphocytes constitutively ...

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