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Protein Regulatory Pathways
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Immune response _IFN gamma signaling pathway [score: 1 (0%)]
Interferons (IFNs) are pleiotropic cytokines that mediate anti-viral responses,
inhibit proliferation and participate in immune surveillance and tumor suppression by
inducing the transcription of a number of IFN-stimulated genes. The IFN family includes
two main classes of related cytokines, type ...
Development_EGFR signaling pathway [score: 1 (0%)]
Epidermal growth factor receptor (EGFR) belongs to the
ERBB family of receptor tyrosine kinases that contains four
closely related members EGFR and ERBB2-4. They couple the
binding of the extracellular growth factor ligands to intracellular signaling pathways
that regulate diverse ...
Development_EPO-induced MAPK pathway [score: 1 (0%)]
Erythropoiesis is the main pathway of pluripotent hematopoietic stem cell development
into mature end stage cells. Erythropoietin (Epo) is a major
lineage-specific hematopoietic growth factor required for survival, proliferation and
differentiation of committed erythroid progenitor cells [
Immune response_CD16 signaling in NK cells [score: 1 (0%)]
Natural killer (NK) cells mediate antibody-depend cellular cytotoxicity through the Fc
fragment of IgG, low affinity IIIa and receptor (CD16a) (Fc gamma RIII
alpha (CD16)) [1], [2]. The preferred ligands
for Fc gamma RIII alpha (CD16) ...
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