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Immune response_IL-2 activation and signaling pathway [score: 1 (0%)]

Interleukin-2 (IL-2) is a T-Cell-derived cytokine important in the regulation of growth and differentiation of T-Cells, B-Cells, natural killer cells, glioma cells, and cells of the monocyte lineage.

IL-2 signaling is mediated by a multichain IL-2 receptor complex consisting ...

Immune response_IL-4 signaling pathway [score: 1 (0%)]

Interleukin-4 (IL-4) is a T cell derived multifunctional cytokine that plays a critical role in the regulation of immune responses. IL-4 induces Th2 (T helper 2) differentiation, causes macrophage suppression, and stimulates B cell production of Immunoglobulins E, G1 and G4 (IgE, ...

Immune response_IL-9 signaling pathway [score: 1 (0%)]

Interleukin-9 (IL-9) is a multifunctional cytokine secreted by T helper 2 (Th2) lymphocytes. IL-9 exerts various effects on a variety of cell types associated with allergic inflammation. IL-9 stimulates the growth and proliferation of T cells, enhances the production of IgE from ...

Immune response_Function of MEF2 in T lymphocytes [score: 1 (0%)]

Myocyte enhancer factors 2 (MEF2) is a family of muscle-enriched transcription factors that have an essential role in myogenesis. In addition, MEF2 is also expressed at high levels in neurons and lymphocytes, where it serves as a regulator of neuronal and immune cell differentiation ...

Immune response_IL-12 signaling pathway [score: 1 (0%)]

IL-12 is a key immunoregulatory cytokine that coordinates innate and adaptive immune response. Major event of IL-12 signaling is activation ...

Immune response_IL-12-induced IFN-gamma production [score: 1 (0%)]

IL-12 is an important cytokine involved in production of IFN-gamma by T cells and NK cells, and plays an important role in T-helper ...

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