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Immune response_IL-2 activation and signaling pathway [score: 1 (0%)]
IL-2 activation and signaling pathway
Interleukin-2 (IL-2) is a T-Cell-derived cytokine
important in the regulation of growth and differentiation of T-Cells, B-Cells, natural
killer cells, glioma cells, and cells of the monocyte lineage.
IL-2 signaling is mediated ...
Immune response_IL-4 signaling pathway [score: 1 (0%)]
IL-4 signaling pathway
Interleukin-4 (IL-4) is a T cell derived multifunctional
cytokine that plays a critical role in the regulation of immune responses.
IL-4 induces Th2 (T helper 2) differentiation, causes
macrophage suppression, and stimulates B cell production of ...
Immune response _IFN gamma signaling pathway [score: 1 (0%)]
Interferon-gamma signaling
Interferons (IFNs) are pleiotropic cytokines that mediate anti-viral responses, inhibit proliferation and participate in immune surveillance and tumor suppression by inducing the transcription of a number of IFN-stimulated genes. The IFN family ...
Development_EGFR signaling pathway [score: 1 (0%)]
EGFR signaling pathway
Epidermal growth factor receptor (EGFR) belongs to the ERBB family of receptor tyrosine kinases that contains four closely related members EGFR and ERBB2-4. They couple the binding of the extracellular growth factor ligands to intracellular ...
Development_Thrombopoetin signaling via JAK-STAT pathway [score: 1 (0%)]
Thrombopoietin signaling pathway
Thrombopoietin is a hormone involved in biological
effects on a broad spectrum of hematopoietic progenitor cells, including stem cells. It
supports stem cell survival and expansion. It is primarily a key physiological regulator
of steady-state ...
Development_TGF-beta receptor signaling [score: 1 (0%)]
TGF-beta receptor signaling
Transforming growth factor beta (TGF-beta) signaling
controls diverse cellular processes, including cell proliferation, differentiation,
adhesion and migration [1], [2], [3].
TGF-beta ...
Immune response_Alternative complement pathway [score: 1 (0%)]
Alternative complement pathway
Complement system is a major effector of humoral branch of the immune system, acting
to protect the host from microorganisms, such as bacteria.
Complement components are designated either by numerals
(C1-C9), letter symbols (e.g.,
Complement ...
Immune response_IL-6 signaling pathway [score: 1 (0%)]
IL-6 signaling pathway
Interleukin-6 (IL-6) is a pleiotropic cytokine produced by
various types of lymphoid and nonlymphoid cells, such as T cells, B
cells, monocytes, fibroblasts, keratinocytes, ...
Immune response_MIF in innate immunity response [score: 1 (0%)]
MIF in innate immunity response
The cytokine Macrophage migration inhibitory factor (MIF) is an
integral mediator of the innate immune system. Monocytes, macrophages
and lymphocytes constitutively ...
Immune response_MIF-JAB1 signaling [score: 1 (0%)]
MIF-JAB1 signaling
Macrophage migration inhibitory factor (MIF) is a pluripotent cytokine involved in inflammation and immune responses as well as in growth factor-dependent cell proliferation, cell cycle, angiogenesis, and tumorigenesis [1], ...
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