 |
|
Refine By Categories
Regulatory Processes
Diseases
Protein Regulatory Pathways
|
 |
|
 |
|
|
Results
|
|
|
 |
| Showing 1 - 10 out of 11 |
Result pages:
1 2 Next |
|
Immune response_IL-4 signaling pathway [score: 1 (0%)]
Interleukin-4 (IL-4) is a T cell derived multifunctional
cytokine that plays a critical role in the regulation of immune responses.
IL-4 induces Th2 (T helper 2) differentiation, causes
macrophage suppression, and stimulates B cell production of Immunoglobulins E, G1 and G4
(IgE, ...
Immune response_Alternative complement pathway [score: 1 (0%)]
Complement system is a major effector of humoral branch of the immune system, acting
to protect the host from microorganisms, such as bacteria.
Complement components are designated either by numerals
(C1-C9), letter symbols (e.g.,
Complement factor I (Factor I)), or by ...
Development_Notch Signaling Pathway [score: 1 (0%)]
Notch homolog 1 translocation-associated (NOTCH1) is
synthesized as NOTCH1 precursor, which is cleaved by
Furin to NOTCH1
receptor form. NOTCH1 receptor
is activated by Jagged [1]. O-fucosylpeptide
3-beta-N-acetylglucosaminyltransferase ...
Development_NOTCH1-mediated pathway for NF-KB activity modulation [score: 1 (0%)]
Interleukin 1 (IL-1) activates Nuclear factor of kappa
light polypeptide gene enhancer in B-cells (NF-KB) via
Interleukin-1 receptor-associated kinase (IRAK) and
Mitogen-activated protein kinase kinase kinase 1
(MEKK1(MAP3K1))-dependent inhibition of nuclear factor of
kappa ...
Immune response_IL-10 signaling pathway [score: 1 (0%)]
Interleukin-10 (IL-10) is a pleiotropic cytokine with
important immunoregulatory functions. Its actions influence activities of many of the
cell-types in the immune system. It is also a cytokine with potent anti-inflammatory
properties: it represses the expression of inflammatory cytokines, ...
Immune response_Lectin induced complement pathway [score: 1 (0%)]
The complement system is the major effector of the humoral branch of the immune
system, acting to protect the host from microorganisms such as bacteria.
Complement components are designated by numerals
(C1-C9), by letter symbols
(e.g., Complement factor I (Factor I)), ...
Development_EPO-induced Jak-STAT pathway [score: 1 (0%)]
Erythropoiesis is a major pathway by which a pluripotent hematopoietic stem cell gives
rise to mature end stage cells. Erythropoietin (EPO) is a
lineage-specific hematopoietic growth factor required for survival, proliferation and
differentiation of committed erythroid progenitor cells [
Development_EPO-induced MAPK pathway [score: 1 (0%)]
Erythropoiesis is the main pathway of pluripotent hematopoietic stem cell development
into mature end stage cells. Erythropoietin (Epo) is a major
lineage-specific hematopoietic growth factor required for survival, proliferation and
differentiation of committed erythroid progenitor cells [
Cytokine production by Th17 cells in CF [score: 1 (0%)]
Cystic Fibrosis (CF) is a potentially lethal genetic disease that typically results in
the development of bronchial inflammation, bronchiectasis, the progressive loss of lung
function and, ultimately, death [1].
CF is caused by genetic defects in Cystic Fibrosis ...
Immune response_Bacterial infections in normal airways [score: 1 (0%)]
The upper airways represent a primary site for the introduction of pathogenic
microorganisms from inspired air. The ciliated epithelium features several powerful
mechanisms for prevention of colonization by inhaled bacteria, thus the lower respiratory
tract usually remains sterile. Toll-like receptors ...
|
|
|
|
|