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Protein Regulatory Pathways
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Development_Prolactin receptor signaling [score: 1 (0%)]
Prolactin is a polypeptide hormone secreted by the
pituitary gland and to a lesser extent by numerous extrapituitary tissues. This hormone
affects a great amount of physiological processes [1]. Numerous biological
functions have been attributed to this hormone's ...
Translation_Insulin regulation of translation [score: 1 (0%)]
Insulin plays an important role in the overall regulation
of protein synthesis. Protein synthesis (mRNA translation) is conventionally divided into
three stages: initiation, elongation and termination. Both initiation and elongation can
be controlled by Insulin.
Insulin ...
Transcription_Androgen Receptor nuclear signaling [score: 1 (0%)]
Androgen is the active metabolic product,
5alpha-Dihydrotestosterone, which is produced from the
transformation of Testosterone catalyzed by the
Steroid-5-alpha-reductase, alpha polypeptides 1 and 2 (S5AR1
and S5AR2) [1], [2]. ...
Development_Growth hormone signaling via PI3K/AKT and MAPK cascades [score: 1 (0%)]
Growth hormone (GH or Somatotropin) is a major
growth-promoting and metabolic regulatory hormone. Interaction of
Somatotropin with Growth hormone receptor
(GHR), by virtue of receptor dimerization, causes activation
of GHR associated cytoplasmic tyrosine kinase, Janus kinase ...
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