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G-protein signaling_N-RAS regulation pathway [score: 1 (0%)]

N-RAS regulation pathway

Neuroblastoma RAS viral (v-ras) oncogene homolog (N-RAS) belongs to Ras family of small GTPases. It serves as a signal transducer from growth factor receptors and activates numerous effector molecules resulting in cell growth, differentiation and survival ...

DNA damage_ATM/ATR regulation of G1/S checkpoint [score: 1 (0%)]

ATM/ATR regulation of G1/S and S/G2 checkpoints

DNA damage checkpoints are biochemical pathways that delay or arrest the cell cycle progression in response to the DNA damage. All eukaryotic ...

Immune response_IL-4 signaling pathway [score: 1 (0%)]

IL-4 signaling pathway

Interleukin-4 (IL-4) is a T cell derived multifunctional cytokine that plays a critical role in the regulation of immune responses. IL-4 induces Th2 (T helper 2) differentiation, ...

Development_Angiotensin signaling via PYK2 [score: 1 (0%)]

Angiotensin activation of MAPKs via Pyk2

Angiotensin II, a major effector peptide of the renin-angiotensin system, is believed to play a critical role in the pathogenesis of cardiovascular remodeling associated with hypertension, heart failure, and atherosclerosis. [1]

Angiotensin ...

Development_FGFR signaling pathway [score: 1 (0%)]

FGFR signaling pathway

Fibroblast growth factor 2 (FGF2) has been implicated in diverse cellular processes, including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, ...

Cell cycle_Regulation of G1/S transition (part 2) [score: 1 (0%)]

Regulation of G1/S transition (part 2)

The commencement of the cell cycle coincides with the production and the stabilization of the Cyclin D. The D-type cyclins are essential ...

Development_TGF-beta receptor signaling [score: 1 (0%)]

TGF-beta receptor signaling

Transforming growth factor beta (TGF-beta) signaling controls diverse cellular processes, including cell proliferation, differentiation, adhesion and migration [1], ...

Immune response_Alternative complement pathway [score: 1 (0%)]

Alternative complement pathway

Complement system is a major effector of humoral branch of the immune system, acting to protect the host from microorganisms, such as bacteria.

Complement components ...

Development_Notch Signaling Pathway [score: 1 (0%)]

Notch Signaling Pathway

Notch homolog 1 translocation-associated (NOTCH1) is synthesized as NOTCH1 precursor, which is cleaved by Furin to NOTCH1 receptor form. NOTCH1 ...

Development_NOTCH1-mediated pathway for NF-KB activity modulation [score: 1 (0%)]

NOTCH1-mediated pathway for NF-KB activity modulation

Interleukin 1 (IL-1) activates Nuclear factor of kappa light polypeptide gene enhancer in B-cells (NF-KB) via Interleukin-1 receptor-associated ...

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