Neuroblastoma RAS viral (v-ras) oncogene homolog (N-RAS)
belongs to Ras family of small GTPases. It serves as a signal transducer from growth
factor receptors and activates numerous effector molecules resulting in cell growth,
differentiation and survival ...
DNA damage checkpoints are biochemical pathways that delay or arrest the cell cycle
progression in response to the DNA damage. All eukaryotic cells have four phases within
the cell cycle, G1, S, G2, and M, and one outside, ...
Interleukin-4 (IL-4) is a T cell derived multifunctional
cytokine that plays a critical role in the regulation of immune responses.
IL-4 induces Th2 (T helper 2) differentiation, causes
macrophage suppression, and stimulates B cell production of ...
Angiotensin II, a major effector peptide of the
renin-angiotensin system, is believed to play a critical role in the pathogenesis of
cardiovascular remodeling associated with hypertension, heart failure, and
The commencement of the cell cycle coincides with the production and the stabilization
of the Cyclin D. The D-type cyclins are essential for
synchronization of the cell cycle machinery with extracellular signals. 
Notch homolog 1 translocation-associated (NOTCH1) is
synthesized as NOTCH1 precursor, which is cleaved by
Furin to NOTCH1receptor form. NOTCH1 receptor
is activated by Jagged . O-fucosylpeptide