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Bacterial infections in CF airways [score: 1 (0%)]
The upper airways represent a primary site for the introduction of pathogenic
microorganisms from inspired air. The ciliated epithelium features several powerful
mechanisms for prevention of colonization by inhaled bacteria, thus the lower respiratory
tract usually remains sterile [1].
Defective ...
Mucin expression in CF via TLRs, EGFR signaling pathways [score: 1 (0%)]
Cystic Fibrosis (CF) is a potentially lethal genetic disease that typically results in
the development of bronchial inflammation, bronchiectasis, the progressive loss of lung
function and ultimately death [1].
CF was initially called "mucoviscidosis" because of ...
Inhibitory action of Lipoxins on neutrophil migration [score: 1 (0%)]
Deregulated neutrophilic inflammation and chronic infection lead to progressive
destruction of the airways in cystic fibrosis (CF). In normal tissues, lipoxins are
endogenous anti-inflammatory lipid mediators in regulation of neutrophilic inflammation
[1]. In CF, production ...
Immune response_Bacterial infections in normal airways [score: 1 (0%)]
The upper airways represent a primary site for the introduction of pathogenic
microorganisms from inspired air. The ciliated epithelium features several powerful
mechanisms for prevention of colonization by inhaled bacteria, thus the lower respiratory
tract usually remains sterile. Toll-like receptors ...
Cytokine production by Th17 cells in CF (Mouse model) [score: 1 (0%)]
Cystic Fibrosis (CF) is a potentially lethal genetic disease that typically results in
the development of bronchial inflammation, bronchiectasis, the progressive loss of lung
function and, ultimately, death [1].
CF is caused by genetic defects in Cystic Fibrosis ...
Classical complement pathway [score: 1 (0%)]
Complement system is a major effector of the humoral branch of the immune system,
acting to protect the host from microorganisms such as bacteria.
Complement components are designated by numerals (C1-C9), by letter symbols (e.g.,
Complement factor I (Factor I)), or by other trivial ...
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