Peroxisome Proliferator-Activated Receptors (PPAR) are ligand-inducible transcription factors that belong to the nuclear hormone receptor superfamily. The PPAR group consists of three types: PPAR-alpha, PPAR-beta(delta) and PPAR-gamma. They have some differences ...

Androgen and Estrogen receptors (Androgen receptor and ESR1 (nuclear)) function as steroid-hormone activated transcription factors. Upon binding the hormone ligand, receptors dissociate from accessory proteins, translocate into the nucleus, dimerize, and then stimulate transcription ...

Sp1 transcription factor (SP1) is a transcription factor involved in gene expression in the early development of an organism. It belongs to the Sp/KLF family of transcription factors. The SP1 transcription factor contains a zinc finger protein motif, by which it binds directly to DNA ...