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Development_Angiotensin signaling via PYK2 [score: 1 (0%)]
Angiotensin activation of MAPKs via Pyk2
Angiotensin II, a major effector peptide of the
renin-angiotensin system, is believed to play a critical role in the pathogenesis of
cardiovascular remodeling associated with hypertension, heart failure, and
atherosclerosis. [ 1] Angiotensin ...
Development_VEGF signaling and activation [score: 1 (0%)]
VEGF signaling and activation
The vascular endothelial growth factor (VEGF) family of ligands and
receptors is crucial for vascular development and neovascularization in
physiological and pathological processes ...
Transcription_PPAR Pathway [score: 1 (0%)]
Peroxisome Proliferator-Activated Receptors
(PPAR) are ligand-inducible transcription factors that belong to the nuclear hormone receptor superfamily. The PPAR group consists of three types: PPAR-alpha, PPAR-beta(delta) and PPAR-gamma. ...
Development_Angiotensin signaling via beta-Arrestin [score: 1 (0%)]
Angiotensin signaling via Beta-arrestin
Angiotensin II, a major effector peptide of the renin-angiotensin
system, is now believed to play a critical role in the pathogenesis of
cardiovascular remodeling ...
Development_Endothelin-1/EDNRA signaling [score: 1 (0%)]
Endothelin-1 signaling via EDNRA
Endothelin-1, a potent endothelium-derived vasoconstrictor
peptide, exerts a growth-promoting effect on vascular smooth muscle
cells, implicating its pathogenic role ...
Development_EDNRB signaling [score: 1 (0%)]
Endothelin receptor type B (
EDNRB) belongs to the guanine
nucleotide binding protein (G-protein) coupled receptor family. Endothelin-1
is most investigated physiological ligand ...
Development_Alpha-2 adrenergic receptor activation of ERK [score: 1 (0%)]
Alpha-2 adrenergic receptor activation of
Alpha-2A adrenergic receptor, Alpha-2B
adrenergic receptor, and Alpha-2C-1 adrenergic
receptor participate in activation of Mitogen-activated protein kinases 1
and 3 ( ERK1/2) via different ways [ 1]. Alpha-2A ...