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Transcription_PPAR Pathway [score: 1 (0%)]

Peroxisome Proliferator-Activated Receptors (PPAR) are ligand-inducible transcription factors that belong to the nuclear hormone receptor superfamily. The PPAR group consists of three types: PPAR-alpha, PPAR-beta(delta) and PPAR-gamma. They have some differences ...

Development_Ligand-independent activation of ESR1 and ESR2 [score: 1 (0%)]

In addition to the conventional hormone-dependent regulation of activity of Estrogen receptor alpha and beta (ESR1(nuclear) and ESR2 respectively), there is a cross-talk between signal transduction pathways and estrogen receptors [1]. Epidermal growth factor (EGF), ...

Selected targets of SP1 [score: 1 (0%)]

Sp1 transcription factor (SP1) is a transcription factor involved in gene expression in the early development of an organism. It belongs to the Sp/KLF family of transcription factors. The SP1 transcription factor contains a zinc finger protein motif, by which it binds directly to DNA ...

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