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Transcription_Mechanism of regulation of the transcription of Retinoid-target genes [score: 1 (0%)]
Mechanism of regulation of the transcription of Retinoid-target genes Abstract:

Retinoic acid binds to cellular Retinoic acid binding proteins, like CRABP2, and enters the nucleus ...

Immune response_MIF-JAB1 signaling [score: 1 (0%)]

MIF-JAB1 signaling

Macrophage migration inhibitory factor (MIF) is a pluripotent cytokine involved in inflammation and immune responses as well as in growth factor-dependent cell proliferation, cell ...

Transcription_PPAR Pathway [score: 1 (0%)]

PPAR Pathway

Peroxisome Proliferator-Activated Receptors (PPAR) are ligand-inducible transcription factors that belong to the nuclear hormone receptor superfamily. The PPAR group consists of ...

Transcription_Role of VDR in regulation of genes involved in osteoporosis [score: 1 (0%)]

Role of VDR in regulation of genes involved in osteoporosis

Osteoporosis is a common disease affecting the majority of older women and a significant minority of older men. It is defined as the gradual reduction ...

Androstenedione and testosterone biosynthesis and metabolism p.1 [score: 1 (0%)]

Androstenedione and testosterone biosynthesis and metabolism part 1

Androstenedione is a 19-carbon steroid hormone produced as an intermediate step in the biochemical pathway that produces the androgen Testosterone ...

Estradiol metabolism [score: 1 (0%)]

Estradiol metabolism.

Endogenous and exogenous estrogens undergo oxidative metabolism by hepatic microsomal cytochrome P-450. Aromatic hydroxylation at either the C2 or C4 position is a major route of Estradiol metabolism in humans and other mammals, although there is less 4-hydroxylation ...

Estrone metabolism [score: 1 (0%)]

Estrone metabolism.

Endogenous and exogenous estrogens undergo oxidative metabolism by hepatic microsomal cytochrome P-450. Aromatic hydroxylation at either the C2 or C4 position is a major route of Estrone ...

Retinol metabolism [score: 1 (0%)]

Retinol metabolism

Key enzymes involved in retinoid metabolisms are alcohol and aldehyde dehydrogenases that convert retinols to aldehydes and aldehydes to carboxylic acids, respectively. The first oxidation ...

Immune response_MIF-mediated glucocorticoid regulation [score: 1 (0%)]

MIF-mediated glucocorticoid regulation

Glucocorticoids are potent anti-inflammatory and immunosuppressive agents. They inhibit synthesis of almost all known cytokines, enzymes involved in the inflammatory process and several cell surface molecules required for immune function. ...

Transcription_Androgen Receptor nuclear signaling [score: 1 (0%)]

Androgen Receptor nuclear signaling

Androgen is the active metabolic product, 5alpha-Dihydrotestosterone, which is produced from the transformation of Testosterone catalyzed by the Steroid-5-alpha-reductase, ...

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