Adenosine A2B receptor influences cell differentiation and proliferation. A2B receptors are G-protein-coupled receptors coupling to classical second messenger pathways, such as modulation of Cyclic Adenosine 3',5'-phosphate (cAMP) production or the Phospholipase ...

Adenosine is a potent biological mediator that affects numerous cell types, including neuronal cells, platelets, neutrophils and smooth muscle cells. Currently, four adenosine receptor subtypes have been identified: A1, A2A, A2B and A3. Adenosine receptors belong to the G-protein-coupled receptor ...

Endothelin receptor type B (EDNRB) belongs to the guanine nucleotide binding protein (G-protein) coupled receptor family. Endothelin-1 is most investigated physiological ligand of EDNRB [1]. EDNRB binds to many types of the G-proteins but the ...

Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and Beta-3 adrenergic receptor are ...

cAMP responsive element binding protein 1 (CREB1) is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. CREB1 binds as a homodimer to the cAMP-responsive element, an octameric palindrome. CREB1 is phosphorylated by several protein kinases, ...