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Regulatory Processes
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Protein Regulatory Pathways
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Translation_Insulin regulation of translation [score: 1 (0%)]
Insulin plays an important role in the overall regulation
of protein synthesis. Protein synthesis (mRNA translation) is conventionally divided into
three stages: initiation, elongation and termination. Both initiation and elongation can
be controlled by Insulin.
Insulin ...
Cell adhesion_Endothelial cell contacts by non-junctional mechanisms [score: 1 (0%)]
Contacts between endothelial cells are of great importance for blood vessel
formation. The formation and maintenance of endothelial cell
contacts require the complex interplay of plasma membrane proteins, cytoskeleton
components, and signaling molecules. Some of these molecules are specifically ...
Development_EPO-induced Jak-STAT pathway [score: 1 (0%)]
Erythropoiesis is a major pathway by which a pluripotent hematopoietic stem cell gives
rise to mature end stage cells. Erythropoietin (EPO) is a
lineage-specific hematopoietic growth factor required for survival, proliferation and
differentiation of committed erythroid progenitor cells [
Development_EPO-induced MAPK pathway [score: 1 (0%)]
Erythropoiesis is the main pathway of pluripotent hematopoietic stem cell development
into mature end stage cells. Erythropoietin (Epo) is a major
lineage-specific hematopoietic growth factor required for survival, proliferation and
differentiation of committed erythroid progenitor cells [
Apoptosis and survival_Lymphotoxin-beta receptor signaling [score: 1 (0%)]
Lymphotoxin-beta receptor (LTBR), a member of the tumor
necrosis factor receptor superfamily, is essential for the development and organization
of secondary lymphoid tissue. The LTBR binds specific
ligands, such as the membrane form of lymphotoxin heterotrimer, Lymphotoxin-Alpha1Beta2
(TNF-beta/LTB ...
Development_Slit-Robo signaling [score: 1 (0%)]
Attractive and repulsive receptors regulate cell motility and attachment in axon
guidance, vascular growth, immune cell regulation and tumor progression. There is strong
evidence that development of the nervous and vascular systems is controlled by common
cues.
Semaphorins, Ephrins, SLITs ...
Transcription_Androgen Receptor nuclear signaling [score: 1 (0%)]
Androgen is the active metabolic product,
5alpha-Dihydrotestosterone, which is produced from the
transformation of Testosterone catalyzed by the
Steroid-5-alpha-reductase, alpha polypeptides 1 and 2 (S5AR1
and S5AR2) [1], [2]. ...
Translation_Non-genomic (rapid) action of Androgen Receptor [score: 1 (0%)]
Androgen is the active metabolic product, 5alpha-Dihydrotestosterone
(DHT), which is produced from the transformation of
Testosterone catalyzed by the Steroid-5-alpha-reductase,
alpha polypeptides 1 and 2 (S5AR1 and
S5AR2) [1], [2]. ...
Immune response_Oncostatin M signaling via MAPK in human cells [score: 1 (0%)]
Oncostatin M is a multifunctional cytokine produced by
activated T lymphocytes, monocytes and microglia. It is structurally and functionally
related to the subfamily of hematopoietic and neurotrophic cytokines known as the
Interleukin 6 (IL6)-type cytokine family [1].
Human ...
Immune response_Oncostatin M signaling via JAK-Stat in human cells [score: 1 (0%)]
Oncostatin M is a multifunctional cytokine produced by
activated T lymphocytes, monocytes, microglia. It is structurally and functionally
related to the subfamily of hematopoietic and neurotrophic cytokines known as the
Interleukin 6 (IL6)-type cytokine family [1].
Human ...
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