Extracellular matrix (ECM) remodeling is involved in normal physiological processes,
such as embryonic development, reproduction, proliferation, cell motility and adhesion,
wound healing, angiogenesis, as well as in disease processes, such as arthritis and
metastasis. Matrix metalloproteinases (MMPs) ...
Contacts between endothelial cells are of great importance for blood vessel
formation.The formation and maintenance of endothelial cell
contacts require the complex interplay of plasma membrane proteins, cytoskeleton
components, and signaling molecules. Some of these molecules are specifically ...
Extracellular matrix (ECM) is composed of several macromolecules bound together in a
complex network. This structure allows cells to adhere, migrate and interact.
Hyaluronic acid, a glycosaminoglycan, is a major component
of ECM. Hyaluronic acid-binding proteins such as hyaluronic
Cytoskeleton of most eukaryotic cells consists of three distinct, yet interconnected,
filament systems: actin filaments,
microtubules and intermediate filaments (IF). IF network is
critically involved in cell shape control and imparts intracellular mechanical
Multicellular organisms are separated from external environment by a layer of
epithelial cells whose integrity is maintained by intercellular junction complexes
composed of tight junctions (TJ), adherens junctions, and desmosomes. Tight cell
junctions serve as a physical barrier to prevent solutes ...
vesicles are classified according to the components of the protein coat that
surrounds them during their genesis and early life cycle of endocytosis. One of the most
common and probably best-characterized classes ...
The cytoskeleton in most eukaryotic cells consists of three distinct, yet
interconnected, filament systems: Actin filaments,
Microtubules and intermediate filaments. Cell assembly is
integrated by the network of intermediate filaments (IFs) and by their interactions with
other cytoskeleton ...