Extracellular matrix (ECM) remodeling is involved in normal physiological processes,
such as embryonic development, reproduction, proliferation, cell motility and adhesion,
wound healing, angiogenesis, as well as in disease processes, such as arthritis and
The cytoskeleton in most eukaryotic cells consists of three distinct, yet
interconnected, filament systems: Actin filaments,
Microtubules and intermediate filaments. Cell assembly is
integrated by the network of intermediate filaments (IFs) and by their ...