Role of Brca1 and Brca2 in DNA Repair
DNA damage-dependent activation of the breast and ovarian cancer susceptibility protein 1 (Brca1) occurs via activation of ataxia telangiectasia mutated serine-protein kinase (ATM) [1] or ataxia telangiectasia ...
Spindle assembly and chromosome separation
The two critical steps for cell reproduction are to duplicate the contents of chromosomes and to segregate them into two daughter cells. ...