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Apoptosis and survival_Caspase cascade [score: 1 (0%)]

Caspase cascade

Caspases are the central components of the apoptotic response. The apoptotic caspases are generally divided into two classes: the initiator caspases, which include ...

Apoptosis and survival_FAS signaling cascades [score: 1 (0%)]

FAS signaling cascade

Death receptors such as FasR belong to a Tumour Necrosis Factor (TNF) superfamily of receptors involved in proliferation, differentiation and apoptosis. FasR is ubiquitously ...

Apoptosis and survival_TNFR1 signaling pathway [score: 1 (0%)]
Role TNF-alpha in apoptosis

The tumor necrosis factor (TNF-alpha) is a potent cytokine produced by many cell types, including macrophages, monocytes, lymphocytes, keratinocytes and fibroblasts, in response ...

Proteolysis_Role of Parkin in the Ubiquitin-Proteasomal Pathway [score: 1 (0%)]

Role of Parkin in the Ubiquitin-Proteasomal Pathway

Parkin is E3-ubiquitin-protein ligase that ubiquitinates itself and specific substrate proteins playing a protective role by sequestering misfolded proteins [1].

E3 ligases are part of the ...

Cell adhesion_ECM remodeling [score: 1 (0%)]

ECM remodeling

Extracellular matrix (ECM) remodeling is involved in normal physiological processes, such as embryonic development, reproduction, proliferation, cell motility and adhesion, wound healing, angiogenesis, as well as in disease processes, such as arthritis and metastasis. ...

Cell adhesion_Cell-matrix glycoconjugates [score: 1 (0%)]

Cell- matrix glycoconjugates

Extracellular matrix (ECM) is composed of several macromolecules bound together in a complex network. This structure allows cells to adhere, migrate and interact. Hyaluronic ...

Immune response_Antigen presentation by MHC class I [score: 1 (0%)]

Antigen presentation by MHC class I

Antigen processing and presentation is the process by which antigen-presenting cells express antigen on their cell surface in a form recognizable by lymphocytes. ...

Blood coagulation [score: 1 (0%)]

Blood coagulation

The haemostatic system maintains blood in a fluid state under normal conditions and responds to vessel injury by the rapid formation of a clot consisting of platelets and Fibrin. The traditional view of the regulation of blood coagulation is that the initiation phase ...

Regulation and function of Amyloid proteins [score: 1 (0%)]

Regulation and function of Amyloid proteins

Amyloid precursor protein (APP) was initially detected in cells of the central nervous system and is considered to be involved in the pathogenesis of Alzheimer's disease [1]. Since then, APP has been ...

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