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Development_FGFR signaling pathway [score: 1 (0%)]

Fibroblast growth factor 2 (FGF2) has been implicated in diverse cellular processes, including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, and proliferation [1].

FGF2 induces biological responses by binding to ...

Cytoskeleton remodeling_Reverse signaling by ephrin B [score: 1 (0%)]

Ephrin receptors and Ephrins are both membrane bound, and following their interaction and clustering, each can transduce signals that regulate cell responses [1].

Ephrin receptors activate reverse signaling through their Ephrin ligands ...

Development_HGF signaling pathway [score: 1 (0%)]

Hepatocyte growth factor/Scatter factor (HGF) is a multifunctional growth factor which induces cell dissociation, migration, protection from apoptosis, proliferation and differentiation [1]. Receptor Met proto-oncogene (HGF receptor (Met)) has tyrosine-kinase ...

Development_IGF-1 receptor signaling [score: 1 (0%)]

The insulin-like growth factor system (IGF system) comprises two receptors: Insulin-like growth factor 1 receptor (IGF-1 receptor) and IGF-IIR with their respective ligands: Insulin-like growth factors 1 and 2 (IGF-1 and IGF-2) and six high-affinity IGF binding proteins (IBP).

The ...

Transcription_PPAR Pathway [score: 1 (0%)]

Peroxisome Proliferator-Activated Receptors (PPAR) are ligand-inducible transcription factors that belong to the nuclear hormone receptor superfamily. The PPAR group consists of three types: PPAR-alpha, PPAR-beta(delta) and PPAR-gamma. They have some differences ...

Chemotaxis_CXCR4 signaling pathway [score: 1 (0%)]

Chemokine (C-X-C motif) receptor-4 (CXCR4) is a G protein-coupled receptor (GPCR). It is the only known receptor for stromal-derived factor-1 (SDF-1), and SDF-1 is the only known ligand for CXCR4 [1].

The CXCR4 is expressed in ...

Development_EGFR signaling via small GTPases [score: 1 (0%)]

The Epidermal growth factor receptor (EGFR) belongs to the ERBB family of receptor tyrosine kinases, which consists of four closely related members: EGFR and v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (ERBB2), ERBB3 ...

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