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G-protein signaling_Ras family GTPases in kinase cascades (schema) [score: 1 (0%)]
Ras family GTPases in kinase cascades

GTPases of the Ras superfamily are activated upon growth factors stimuli and controls a wide range of essential biochemical pathways in all eukaryotic cells. One of the most ...

G-protein signaling_Regulation of RAC1 activity [score: 1 (0%)]

Regulation of Rac1 activation

Ras-related C3 botulinum toxin substrate 1 (Rac1) belongs to the Rho subgroup of a family of small GTP-binding proteins (G-proteins) called monomeric G-proteins. Proteins belonging to the Rho subgroup are involved in cytoskeletal control, regulation ...

G-protein signaling_N-RAS regulation pathway [score: 1 (0%)]

N-RAS regulation pathway

Neuroblastoma RAS viral (v-ras) oncogene homolog (N-RAS) belongs to Ras family of small GTPases. It serves as a signal transducer from growth factor receptors and activates numerous effector molecules resulting in cell growth, differentiation and survival ...

Transcription_CREB pathway [score: 1 (0%)]
CREB signaling pathway

Extracellular stimuli elicit changes in gene expression in target cells by activating intracellular protein kinase cascades that phosphorylate transcription factors within the nucleus. One of the best characterized stimulus-induced transcription factors ...

Immune response_IL-2 activation and signaling pathway [score: 1 (0%)]

IL-2 activation and signaling pathway

Interleukin-2 (IL-2) is a T-Cell-derived cytokine important in the regulation of growth and differentiation of T-Cells, B-Cells, natural killer cells, glioma cells, and cells of the monocyte lineage.

IL-2 signaling is mediated ...

Immune response_T cell receptor signaling pathway [score: 1 (0%)]

T cell receptor signaling pathway

T cell receptors (TCR) play a key role in functioning of T cells and formation of the immunological synapse. It provides connection between T cell and the antigen-presenting ...

Development_FGFR signaling pathway [score: 1 (0%)]

FGFR signaling pathway

Fibroblast growth factor 2 (FGF2) has been implicated in diverse cellular processes, including apoptosis, cell survival, chemotaxis, cell adhesion, migration, differentiation, ...

Development_VEGF-family signaling [score: 1 (0%)]

VEGF-family signaling

The vascular endothelial growth factor (VEGF) family of ligands and receptors is crucial for vascular development and neovascularization in physiological and pathological processes ...

Cytoskeleton remodeling_FAK signaling [score: 1 (0%)]
FAK signaling

The biological importance of PTK2 protein tyrosine kinase 2, or Focal adhesion kinase 1 (FAK1)-mediated signal transduction is underscored by the fact that this tyrosine kinase plays a fundamental role in embryonic development, in control of cell migration, ...

Cell adhesion_Integrin-mediated cell adhesion and migration [score: 1 (0%)]

Integrin-mediated cell adhesion and migration

Cell migration is a coordinated process that involves rapid changes in the dynamics of actin filaments, together with the formation and disassembly of ...

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