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Immune response_IL-6 signaling pathway [score: 1 (0%)]

Interleukin-6 (IL-6) is a pleiotropic cytokine produced by various types of lymphoid and nonlymphoid cells, such as T cells, B cells, monocytes, fibroblasts, keratinocytes, endothelial cells, mesangial cells and several tumor cells. IL-6 provokes a broad range of cellular and physiological responses, ...

Immune response_IL-22 signaling pathway [score: 1 (0%)]

Interleukin-22 (IL-22) is a member of the IL-10 family of cytokines. The major sources of IL-22 are activated T cells, especially upon type 1 polarization, and natural killer (NK) cells [1], [2].

IL-22 acts via a ...

Immune response_IL-1 signaling pathway [score: 1 (0%)]

Interleukin-1 (IL-1) is a proinflammatory cytokine produced by activated macrophages, endothelial cells, B cells and fibroblasts. IL-1 stimulates a broad spectrum of immune and inflammatory responses [1], [2].

There are two forms of ...

Immune response_Oncostatin M signaling via MAPK in human cells [score: 1 (0%)]

Oncostatin M is a multifunctional cytokine produced by activated T lymphocytes, monocytes and microglia. It is structurally and functionally related to the subfamily of hematopoietic and neurotrophic cytokines known as the Interleukin 6 (IL6)-type cytokine family [1].

Human ...

Immune response_IL-12-induced IFN-gamma production [score: 1 (0%)]

IL-12 is an important cytokine involved in production of IFN-gamma by T cells and NK cells, and plays an important role in T-helper ...

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