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Chemotaxis_CXCR4 signaling pathway [score: 1 (0%)]

Chemokine (C-X-C motif) receptor-4 (CXCR4) is a G protein-coupled receptor (GPCR). It is the only known receptor for stromal-derived factor-1 (SDF-1), and SDF-1 is the only known ligand for CXCR4 [1].

The CXCR4 is expressed in ...

Immune response _CCR3 signaling in eosinophils [score: 1 (0%)]

Human eosinophils are key effector cells implicated in a number of chronic inflammatory reactions, associated with bronchial asthma, allergic-inflammatory diseases and parasitic infections. Chemoattractants/chemokines, generated at the affected sites, promote migration of eosinophils from vasculature ...

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