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Immune response_IL-2 activation and signaling pathway [score: 1 (0%)]
IL-2 activation and signaling pathway
IL-2) is a T-Cell-derived cytokine
important in the regulation of growth and differentiation of T-Cells, B-Cells, natural
killer cells, glioma cells, and cells of the monocyte lineage. IL-2 signaling is mediated ...
Immune response_IL-4 signaling pathway [score: 1 (0%)]
IL-4 signaling pathway
IL-4) is a T cell derived multifunctional cytokine
that plays a critical role in the regulation of immune responses. IL-4
induces Th2 (T helper 2) differentiation, ...
Immune response _IFN gamma signaling pathway [score: 1 (0%)]
Interferons (IFNs) are pleiotropic cytokines that mediate anti-viral
responses, inhibit proliferation and participate in immune surveillance
and tumor suppression by inducing the ...
Immune response_IL-6 signaling pathway [score: 1 (0%)]
IL-6 signaling pathway
IL-6) is a pleiotropic cytokine produced by
various types of lymphoid and nonlymphoid cells, such as T cells, B
cells, monocytes, fibroblasts, keratinocytes, ...
Immune response_IL-22 signaling pathway [score: 1 (0%)]
IL-22 signaling pathway
IL-22) is a member of the IL-10 family of
cytokines. The major sources of IL-22 are activated T cells,
especially upon type 1 polarization, and natural ...
Immune response_IL-9 signaling pathway [score: 1 (0%)]
IL-9 signaling pathway
IL-9) is a multifunctional cytokine secreted by T
helper 2 (Th2) lymphocytes. IL-9 exerts various effects on a
variety of cell types associated with allergic ...
Immune response_IL-10 signaling pathway [score: 1 (0%)]
IL-10 signaling pathway
IL-10) is a pleiotropic cytokine with
important immunoregulatory functions. Its actions influence activities of many of the
cell-types in the immune system. It is also a cytokine with potent anti-inflammatory
properties: it represses the ...
Chemotaxis_CXCR4 signaling pathway [score: 1 (0%)]
CXCR4 signaling via small GTPases
Chemokine (C-X-C motif) receptor-4 (
CXCR4) is a G protein-coupled
receptor (GPCR). It is the only known receptor for stromal-derived
factor-1 ( SDF-1), and ...
Immune response_IL-1 signaling pathway [score: 1 (0%)]
IL-1 signaling pathway
Interleukin-1 (IL-1) is a proinflammatory cytokine produced by activated
macrophages, endothelial cells, B cells and fibroblasts. IL-1 stimulates
a broad spectrum of immune and inflammatory ...
Immune response _CCR3 signaling in eosinophils [score: 1 (0%)]
CCR3 signaling in eosinophils
Human eosinophils are key effector cells implicated in a number of
chronic inflammatory reactions, associated with bronchial asthma,
allergic-inflammatory diseases and parasitic ...