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Protein Regulatory Pathways
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G-protein signaling_N-RAS regulation pathway [score: 1 (0%)]
Neuroblastoma RAS viral (v-ras) oncogene homolog (N-RAS)
belongs to Ras family of small GTPases. It serves as a signal transducer from growth
factor receptors and activates numerous effector molecules resulting in cell growth,
differentiation and survival [1], [
Transcription_CREB pathway [score: 1 (0%)]
Extracellular stimuli elicit changes in gene expression in target cells by activating
intracellular protein kinase cascades that phosphorylate transcription factors within the
nucleus. One of the best characterized stimulus-induced transcription factors is cyclic
AMP (cAMP) responsive element binding ...
Signal transduction_Erk Interactions: Inhibition of Erk [score: 1 (0%)]
Mitogen-activated protein kinase (MAPK) pathways regulate a variety of physiological
processes, such as cell growth, differentiation, and apoptotic cell death. To date, three
MAPK pathways have been characterized in detail. The extracellular regulated kinase (ERK)
pathway is activated by a large ...
Signal transduction_PKA signaling [score: 1 (0%)]
Protein kinase cAMP-dependent (PKA) is an enzyme playing
key role in a number of cellular processes. In its inactivated state,
PKA exists as a tetrameric complex of two catalytic subunits
(PKA-cat alpha and PKA-cat
beta) and two regulatory subunits (PKA-reg) (alpha ...
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