 |
|
Refine By Categories
Regulatory Processes
Diseases
Protein Regulatory Pathways
|
 |
|
 |
|
|
Results
|
|
|
 |
| Showing 1 - 10 out of 10 |
Result pages:
1 |
|
Development_Angiotensin signaling via PYK2 [score: 1 (0%)]
Angiotensin II, a major effector peptide of the
renin-angiotensin system, is believed to play a critical role in the pathogenesis of
cardiovascular remodeling associated with hypertension, heart failure, and
atherosclerosis. [1]
Angiotensin II receptor, ...
Development_VEGF signaling via VEGFR2 - generic cascades [score: 1 (0%)]
VEGF family of ligands and receptors is crucial for vascular development and
neovascularization in physiological and pathological processes in both embryo and adult.
VEGFR-2 is a high-affinity receptor for
VEGF-A. Activated VEGFR-2 can
activate p38 MAPK, PI3K reg class
IA/ ...
Development_Angiotensin signaling via beta-Arrestin [score: 1 (0%)]
Angiotensin II, a major effector peptide of the
renin-angiotensin system, is now believed to play a critical role in the pathogenesis of
cardiovascular remodeling associated with hypertension, heart failure, and
atherosclerosis [1].
Angiotensin II receptor ...
Development_Endothelin-1/EDNRA signaling [score: 1 (0%)]
Endothelin-1, a potent endothelium-derived
vasoconstrictor peptide, exerts a growth-promoting effect on vascular smooth muscle
cells, implicating its pathogenic role in vascular remodeling.
Endothelin-1 action is exerted by its binding to Endothelin
receptor type A (EDNRA) [
Development_EDNRB signaling [score: 1 (0%)]
Endothelin receptor type B (EDNRB) belongs to the guanine
nucleotide binding protein (G-protein) coupled receptor family.
Endothelin-1 is most investigated physiological ligand of
EDNRB [1]. EDNRB
binds to many types of the G-proteins but the ...
Development_Activation of ERK by Alpha-1 adrenergic receptors [score: 1 (0%)]
Subtype alpha-1 adrenergic receptors consists of Alpha-1A adrenergic
receptor, Alpha-1B adrenergic receptor and
Alpha-1D adrenergic receptor. They participate in many
physiological processes via different pathways. One of the best studied alpha-1
adrenergic receptors-stimulated ...
Development_Alpha-2 adrenergic receptor activation of ERK [score: 1 (0%)]
Alpha-2A adrenergic receptor, Alpha-2B
adrenergic receptor, and Alpha-2C-1 adrenergic
receptor participate in activation of Mitogen-activated protein kinases 1
and 3 (ERK1/2) via different ways [1].
Alpha-2A adrenergic receptor ...
Selected targets of C/EBP [score: 1 (0%)]
CCAAT/enhancer binding proteins (C/EBP) are a group of
bZIP transcription factors, consisting of C/EBPalpha,
beta, delta,
epsilon, gamma and
zeta, which can bind as homodimers to certain promoters and
enhancers. C/EBP is important in the regulation ...
Angiotensin activation of ERK [score: 1 (0%)]
Angiotensin II, a major effector peptide of the
renin-angiotensin system, and is believed to play a critical role in the pathogenesis of
cardiovascular remodeling associated with hypertension, heart failure, and
atherosclerosis [1]. Angiotensin II acts via
Angiotensin ...
|
|
|
|
|