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G-protein signaling_N-RAS regulation pathway [score: 1 (0%)]

N-RAS regulation pathway

Neuroblastoma RAS viral (v-ras) oncogene homolog (N-RAS) belongs to Ras family of small GTPases. It serves as a signal transducer from growth factor receptors and activates numerous effector molecules resulting in cell growth, differentiation and survival ...

Transcription_CREB pathway [score: 1 (0%)]
CREB signaling pathway

Extracellular stimuli elicit changes in gene expression in target cells by activating intracellular protein kinase cascades that phosphorylate transcription factors within the nucleus. One of the best characterized stimulus-induced transcription factors ...

Immune response _IFN gamma signaling pathway [score: 1 (0%)]

Interferon-gamma signaling

Interferons (IFNs) are pleiotropic cytokines that mediate anti-viral responses, inhibit proliferation and participate in immune surveillance and tumor suppression by inducing the ...

Immune response_T cell receptor signaling pathway [score: 1 (0%)]

T cell receptor signaling pathway

T cell receptors (TCR) play a key role in functioning of T cells and formation of the immunological synapse. It provides connection between T cell and the antigen-presenting ...

Development_Angiotensin signaling via PYK2 [score: 1 (0%)]

Angiotensin activation of MAPKs via Pyk2

Angiotensin II, a major effector peptide of the renin-angiotensin system, is believed to play a critical role in the pathogenesis of cardiovascular remodeling associated with hypertension, heart failure, and atherosclerosis. [1]

Angiotensin ...

Development_Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis [score: 1 (0%)]

Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis

There are two families of transcription factors that play pivotal roles during mammalian skeletal muscle differentiation. ...

Signal transduction_Erk Interactions: Inhibition of Erk [score: 1 (0%)]

Erk Interactions: Inhibition of Erk

Mitogen-activated protein kinase (MAPK) pathways regulate a variety of physiological processes, such as cell growth, differentiation, and apoptotic cell death. To date, ...

Cytoskeleton remodeling_FAK signaling [score: 1 (0%)]
FAK signaling

The biological importance of PTK2 protein tyrosine kinase 2, or Focal adhesion kinase 1 (FAK1)-mediated signal transduction is underscored by the fact that this tyrosine kinase plays a fundamental role in embryonic development, in control of cell migration, ...

Signal transduction_Activation of PKC via G-Protein coupled receptor [score: 1 (0%)]

PKC family signaling

The family of Protein kinase C (PKC) contains 3 functional protein types, "conventional" PKC-alpha, PKC-beta, and PKC-gamma that are activated by calcium and Diacylglycerol (DAG), "novel" PKC-delta, PKC-epsilon, PKC-eta, ...

Development_G-Proteins mediated regulation MAPK-ERK signaling [score: 1 (0%)]

G-protein-mediated regulation of MAPK-ERK signaling

Guanine nucleotide binding protein (G-proteins) are heterotrimeric signaling molecules composed of three subunits, alpha, beta, and gamma, which ...

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