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Protein Regulatory Pathways
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G-protein signaling_N-RAS regulation pathway [score: 1 (0%)]
N-RAS regulation pathway
Neuroblastoma RAS viral (v-ras) oncogene homolog (N-RAS)
belongs to Ras family of small GTPases. It serves as a signal transducer from growth
factor receptors and activates numerous effector molecules resulting in cell growth,
differentiation and survival ...
Transcription_CREB pathway [score: 1 (0%)]
CREB signaling pathway
Extracellular stimuli elicit changes in gene expression in target cells
by activating intracellular protein kinase cascades that phosphorylate
transcription factors within the nucleus. ...
Immune response _IFN gamma signaling pathway [score: 1 (0%)]
Interferon-gamma signaling
Interferons (IFNs) are pleiotropic cytokines that mediate anti-viral responses, inhibit proliferation and participate in immune surveillance and tumor suppression by inducing the transcription of a number of IFN-stimulated genes. The IFN family ...
Immune response_T cell receptor signaling pathway [score: 1 (0%)]
T cell receptor signaling pathway
T cell receptors (TCR) play a key role in functioning of T cells
and formation of the immunological synapse. It provides connection
between T cell and the antigen-presenting ...
Development_Angiotensin signaling via PYK2 [score: 1 (0%)]
Angiotensin activation of MAPKs via Pyk2
Angiotensin II, a major effector peptide of the
renin-angiotensin system, is believed to play a critical role in the pathogenesis of
cardiovascular remodeling associated with hypertension, heart failure, and
atherosclerosis. [1]
Angiotensin ...
Signal transduction_Erk Interactions: Inhibition of Erk [score: 1 (0%)]
Erk Interactions: Inhibition of Erk
Mitogen-activated protein kinase (MAPK) pathways regulate a variety of
physiological processes, such as cell growth, differentiation, and
apoptotic cell death. To date, ...
Cytoskeleton remodeling_FAK signaling [score: 1 (0%)]
FAK signaling
The biological importance of PTK2 protein tyrosine kinase 2, or Focal
adhesion kinase 1 (FAK1)-mediated signal transduction is
underscored by the fact that this tyrosine kinase plays a fundamental role in embryonic
development, in control of cell migration, cell ...
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