Covance’s Genomics Laboratory and the Institute for Systems Biology Collaborate to Further Research in Tumor Biology

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PRINCETON, N.J., March 8, 2011 — Covance Inc. (NYSE: CVD) today announced that its Seattle-based genomics laboratory (www.covance.com/cgl) has initiated a collaboration with the Institute for Systems Biology (ISB) to further understand the area of brain tumor biology. Covance, a leading provider of genomics solutions for the drug discovery and development industry, and ISB, the leader in understanding complex biological systems, plan to work collectively to unravel the complex regulation of gene expression in Glioblastoma multiforme (GBM), one of the most aggressive forms of brain cancer.

This research project will bring together Covance’s expertise in genomics assays and ISB’s expertise in complex genomic networks.
Having run more than 450,000 samples to date, Covance’s genomics laboratory provides end-to-end services for genomics-based development research and has demonstrated particular expertise in Next Generation Sequencing (NGS). NGS will be used to provide researchers an important dataset to investigate tumor heterogeneity and find targets for patient stratification and/or therapeutics. The goal of the collaboration is to enable research in brain tumor biology by providing a high-quality map of gene expression and RNA structure.

“We are delighted to be working with the ISB on this high value project, helping to empower research for this unmet medical need,” said Thomas Turi Ph.D., Vice President of Science and Technology for Covance Discovery and Translational Services. “By applying Covance’s expertise in genomics, guided by ISB’s expertise in analyzing integrated biological networks, we will gain a greater understanding of Glioblastoma multiforme.”

“Collaborating with Covance will help us better understand the disease of Glioblastoma multiforme biology” said Lee Hood M.D., Ph.D., President of the Institute for Systems Biology. “The ability to resolve complex regulatory networks requires reproducible, high-quality data. We know Covance’s experience in genomics and Next Generation Sequencing will give us an unprecedented level of high-quality data.” 

About Covance
Covance, with headquarters in
Princeton, New Jersey, is one of the world’s largest and most comprehensive drug development services companies with annual revenues greater than $1.9 billion, global operations in more than 30 countries, and more than 10,000 employees worldwide. Information on Covance’s products and services, recent press releases, and SEC filings can be obtained through its website at www.covance.com.


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