ICH Supplemental Tests

In-depth studies with a team well versed in ICH guidelines.

As a part of ICH studies, you may need to do more in-depth studies on the core battery organ systems. Here are some of the ways we go further to better understand the impact of your molecule on the heart:

  • hERG trafficking assay
  • Cardiac contractility (LVP)
  • Langendorff Isolated Heart model
  • Purkinje fiber assay
  • Echocardiography

Supplemental studies can also be conducted on the GI, renal and CNS systems — including abuse and seizure liability assessment. 

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