Regulatory Assays

Providing assays for proactive insights.

We provide a complete range of assays to determine the potential genetic toxicity of your novel drug, chemical or cosmetic. Our scientists have done this long before guidelines even existed. We conduct hundreds of assays to meet regulatory guidelines and GLP standards each year. Here are the most common.

Regulatory Assays at Covance

Toxicology Services & Tests

Hazard Identification

(in vitro)

Hazard Evaluation & Risk Assessment

(in vivo)

Ames test

*

 

Gene mutation

*

 

Chromosomal aberration

*

 

Micronucleus

**

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Comet

*

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Combined micronucleus/Comet

 

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Non-disjunction testing using FISH or antikinetochore

*

 

Cytotoxicity & phototoxicity

*

 

Clinical trial & occupational cytogenetics monitoring

*

 

EPISKIN™

*

 

EpiDerm™

*

 

Eye irritation (BCOP)

*

 

Rodent bone marrow cytogenetics

 

*

Transgenic rodent mutation assays (Muta™Mouse)

 

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