Neurotoxicity Study Services

A meeting of the minds to ensure your molecule’s safety.

We have a number of senior staff members who are active in the fast-moving field of neuroscience. We partner with you to develop, optimize and implement innovative techniques to evaluate the potential toxicity effects of your molecule on the nervous system.

Neurotoxicity Study Services at Covance

We offer a wide range of techniques for neurotoxicology assessment including:

  • EPA acute neurotoxicity battery
  • Subchronic neurotoxicity
  • Behavioral testing
  • Abuse liability
  • Seizure liability
  • Developmental neurotoxicity
  • Nerve conductance test
  • EthoVision™

Abuse liability. A crucial step if your molecule has a central nervous system effect.

Our team first evaluates the mechanism of action, pharmacokinetics data, and active metabolites, based on the target population. We then outline a study plan that provides all the necessary testing and documentation required for regulatory reporting. Specific services include:

  • Neuropharmacological characterization
  • Receptor binding
  • Animal behavioral data
  • Neurobehavioral effects
  • Discriminative effects
  • Reinforcing effects
  • Physical dependence
  • Tolerance